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Further, kinetic studies of seleno-GPxs have revealed that the rate constant for the reaction of hydroperoxides with the selenolate of Sec is twothree orders of magnitude higher than the combined rate constant of the successive reactions of selenenic acid with the two molecules of GSH [8,9,10,11,12,13,14,15,16,17,18]

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2011a), which are primary sources of oxidative stress during an invertebrate immune response (Nappi and Ottaviani 2000

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